Is asthma only an airways disorder?

Is asthma a vascular disorder?

Human allergic asthma is defined as a chronic inflammatory disorder of the airways and is characterised by airway inflammation, persistent airways hyperresponsiveness (AHR)

Human allergic asthma is defined as a chronic inflammatory disorder of the airways and is characterised by airway inflammation, persistent airways hyperresponsiveness (AHR) and intermittent, reversible airways obstruction (GINA, 2006; Bousquet et al., 2000). In addition, structural changes in the airway including subepithelial and airway wall fibrosis, goblet cell hyperplasia/metaplasia, smooth...

Asthma is a Serious Danger

  میزان مرگ و میر آسم طی دهه گذشته بطور چشمگیری تغییر کرده است. با مبتلا کردن ۱۵ میلیون آمریکایی میزان مرگ و میر در سال ۱۹۷۸، به رقم ۱۸۷۲ نفر و ۹ سال بعد، به بیش از ۴۰۰۰ نفر رسید. علت چنین افزایش چشمگیری روشن نیست. علل احتمالی عبارتند از کاهش ظرفیت تنفس، استفاده بیش از حد از داروهای استثنائی و استنباط غلط بیماران و نیز مراکز درمانی نسبت به شدت بیماری است. بررسی دقیق، معالجات مناسب و آموزش به ب...

Small airways diseases, excluding asthma and COPD: an overview.

This review is the summary of a workshop on small airways disease, which took place in Porquerolles, France in November 2011. The purpose of this workshop was to review the evidence on small airways (bronchiolar) involvement under various pathophysiological circumstances, excluding asthma and chronic obstructive pulmonary disease. Histopathological patterns associated with small airways disease...

Asthma is a complex genetic disorder

affected by a myriad of environmental stimuli, leading to suggestions that asthma is not a single disease but a syndrome of related diseases – a situation that complicates the development of relevant animal models (Busse and Lemanske, 2001; Drazen et al., 2000). Asthma is characterized by chronic airway inflammation, airway hyperresponsiveness (AHR) and reversible airflow obstruction. These thr...